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Jaclyn A Biegel Selected Research

Glioma (Gliomas)

5/2023Addendum: Sustained response of three pediatric BRAFV600E mutated high-grade gliomas to combined BRAF and MEK inhibitor therapy.
1/2021The spectrum of mitochondrial DNA (mtDNA) mutations in pediatric CNS tumors.
1/2019Sustained response of three pediatric BRAFV600E mutated high-grade gliomas to combined BRAF and MEK inhibitor therapy.
3/2015Chromosome band 7q34 deletions resulting in KIAA1549-BRAF and FAM131B-BRAF fusions in pediatric low-grade Gliomas.
7/2010Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas.

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Jaclyn A Biegel Research Topics

Disease

46Neoplasms (Cancer)
05/2024 - 08/2002
14Rhabdoid Tumor (Rhabdoid Tumors)
05/2022 - 01/2002
5Glioma (Gliomas)
05/2023 - 07/2010
4Neuroepithelial Neoplasms (Gliomatosis Cerebri)
01/2021 - 07/2010
3Medulloblastoma
04/2024 - 01/2002
3Brain Neoplasms (Brain Tumor)
01/2021 - 07/2004
3Typical Teratoid Rhabdoid Tumor
10/2020 - 07/2004
3Sarcoma (Soft Tissue Sarcoma)
06/2015 - 01/2012
3Astrocytoma (Pilocytic Astrocytoma)
04/2014 - 07/2009
2Central Nervous System Neoplasms
11/2023 - 01/2023
2Leukemia
01/2021 - 01/2015
2Neoplasm Metastasis (Metastasis)
01/2019 - 04/2005
2Neurilemmoma (Schwannoma)
12/2015 - 01/2012
2Carcinoma (Carcinomatosis)
06/2015 - 12/2012
2Carcinogenesis
02/2015 - 01/2011
2Rhabdomyosarcoma
12/2012 - 07/2009
2Neuroblastoma
01/2012 - 08/2005
1Chordoma
05/2024
1Ewing Sarcoma (Sarcoma, Ewing)
11/2022
1Uveal melanoma
06/2022
1Hepatoblastoma
05/2022
1Retinoblastoma (Glioblastoma, Retinal)
03/2021
1Lipoma (Lipomata)
01/2021
1Meningioma (Meningiomas)
01/2021
1Disease Progression
01/2021
1Hemimegalencephaly
01/2021
1Melanoma (Melanoma, Malignant)
01/2019
1Myelodysplastic Syndromes (Myelodysplastic Syndrome)
01/2016
1Inborn Genetic Diseases (Disease, Hereditary)
12/2015
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2015
1Aplastic Anemia (Anemia, Hypoplastic)
10/2013
1Neurofibrosarcoma (MPNST)
01/2012
1Congenital Heart Defects (Congenital Heart Defect)
11/2011
1Hematologic Neoplasms (Hematological Malignancy)
01/2011
1Ganglioglioma
07/2010
1Carcinosarcoma
06/2007
1Primitive Neuroectodermal Tumors (PNET)
08/2006
1Choroid Plexus Carcinoma
05/2005
1Second Primary Neoplasms (Neoplasms, Second)
12/2003

Drug/Important Bio-Agent (IBA)

16DNA (Deoxyribonucleic Acid)IBA
10/2023 - 08/2002
10Proteins (Proteins, Gene)FDA Link
05/2022 - 05/2005
7OligonucleotidesIBA
01/2012 - 03/2009
5Mitochondrial DNA (mtDNA)IBA
05/2024 - 01/2019
4Biomarkers (Surrogate Marker)IBA
06/2022 - 01/2012
4ChromatinIBA
04/2022 - 01/2009
4SMARCB1 ProteinIBA
06/2015 - 01/2012
3RNA (Ribonucleic Acid)IBA
11/2023 - 01/2006
3Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
05/2023 - 02/2015
3Sucrose (Saccharose)IBA
05/2022 - 12/2015
3ParaffinIBA
01/2021 - 03/2013
3Formaldehyde (Formol)FDA Link
01/2021 - 03/2013
3Mitogen-Activated Protein KinasesIBA
03/2015 - 07/2009
22,6-dinitrotoluene (DNT)IBA
03/2015 - 04/2014
2MicroRNAs (MicroRNA)IBA
02/2015 - 01/2011
2Histones (Histone)IBA
01/2011 - 01/2009
2Codon (Codons)IBA
07/2010 - 11/2002
1NAD (NADH)IBA
05/2024
1Circulating Tumor DNAIBA
04/2024
1Cell-Free Nucleic AcidsIBA
01/2023
1Adenosine Triphosphate (ATP)IBA
05/2022
1beta CateninIBA
05/2022
1Keratins (Keratin)IBA
04/2022
1GlypicansIBA
04/2022
1Mucin-1 (CA 15-3 Antigen)IBA
04/2022
1TFXIBA
07/2021
1Genetic Markers (Genetic Marker)IBA
01/2021
1Met Transfer RNAIBA
01/2019
1Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA
06/2015
1MitogensIBA
02/2015
1Phosphotransferases (Kinase)IBA
02/2015
1AZD 6244IBA
02/2015
1EpitopesIBA
10/2013
1Glutathione Transferase (Glutathione S-Transferase)IBA
10/2013
1PlasticsIBA
04/2012
1claudin 6IBA
01/2012
1Cyclin-Dependent Kinase Inhibitor p16IBA
07/2011
1Tumor Suppressor Protein p14ARF (p14ARF)IBA
07/2011
1A-factor (Streptomyces)IBA
01/2011
1Anaplastic Lymphoma KinaseIBA
07/2009
1Histone Deacetylase InhibitorsIBA
01/2009
1romidepsin (FK228)FDA Link
01/2009
1Indicators and Reagents (Reagents)IBA
01/2009
1Cyclin D1IBA
06/2007
1cytidylyl-(3'-5')-cytidine (CpC)IBA
05/2005
1AntigensIBA
01/2005
1CytosineIBA
11/2002
1hydrogen sulfite (bisulfite)IBA
08/2002
1Cytosine NucleotidesIBA
08/2002

Therapy/Procedure

15Therapeutics
05/2023 - 01/2002
4Ligation
10/2023 - 03/2009
4Drug Therapy (Chemotherapy)
10/2020 - 01/2002
1Operative Surgical Procedures
08/2007
1Steam Bath (Sauna)
08/2006
1Radiotherapy
01/2002